What does a high amplitude of R waves in leads V5 and V6 indicate?

A high amplitude of R waves in leads V5 and V6 is indicative of left ventricular hypertrophy (LVH). This happens because the left ventricle is responsible for pumping blood to the entire body and may become enlarged or thickened due to increased workload or pressure. In the context of an electrocardiogram (EKG), this enlargement manifests as taller R waves in the lateral leads, specifically V5 and V6, where electrical activity from the left ventricle is most prominently recorded.

When the heart muscle thickens, it generates a stronger electrical signal, resulting in higher voltage readings in these leads. This is a common finding in conditions associated with chronic hypertension or aortic stenosis, where the left ventricle is subjected to greater stress. Recognizing the high amplitude in these leads is essential for the diagnosis of LVH and can guide further evaluation and management of underlying conditions affecting cardiac health.